[25 April 2013]
Products Affected - Description
Astramorph (preservative-free) injection, APP
0.5 mg/mL 2 mL ampule, 10 count (NDC 63323-0291-80)
0.5 mg/mL 10 mL vial, 5 count (NDC 63323-0291-10)
0.5 mg/mL 10 mL ampule (NDC 63323-0291-97)
1 mg/mL 2 mL ampule, 10 count (NDC 63323-0292-80)
1 mg/mL, 10 mL vial (NDC 63323-0292-10)
1 mg/mL 10 mL ampule (NDC 63323-0292-97)
Morphine injection, Hospira
0.5 mg/mL 10 mL, preservative-free vial (NDC 00409-3814-12)
1 mg/mL 10 mL preservative-free vial (NDC 00409-3815-12)
25 mg/mL 4 mL Add-Vantage vial (NDC 00409-6177-14)
25 mg/mL, 1 mL preservative-free vial (NDC 00409-1135-02)
25 mg/mL, 10 mL Add-Vantage vial (NDC 00409-6179-14 )
50 mg/mL, 20 mL vial (NDC 00409-1134-03)
1 mg/mL, 30 mL PCA vial (NDC 00409-2029-02)
Duramorph (preservative-free), West-Ward
0.5 mg/mL, 10 mL ampules (NDC 00641-6020-10)
Infumorph (preservative-free), West-Ward
25 mg/mL, 20 mL ampule (NDC 00641-6040-01)
10 mg/mL, 20 mL ampule (NDC 00641-6039-01)
Reason for the Shortage
- APP states the shortage is due to a change in manufacturing sites.
- Hospira states the shortage is due to manufacturing delays.
- Hospira discontinued preservative-containing Carpuject syringes in August, 2012 and replaced them with preservative-free Carpuject syringes.
- West-Ward states the shortage is due to increased demand for product. West-Ward changed old Baxter to new West-Ward NDC codes in early 2012.
- IMS (Amphastar) discontinued morphine 1 mg/mL 10 mL Luer-lock syringes in March, 2012 due to low demand for the product.
Available Products
Morphine Injection, Hospira
2 mg/mL, 1 mL preservative-free Carpuject syringe (NDC 00409-1890-01)
4 mg/mL, 1 mL preservative-free Carpuject syringe (NDC 00409-1891-01)
8 mg/mL, 1 mL preservative-free Carpuject syringe (NDC 00409-1892-01)
10 mg/mL, 1 mL preservative-free Carpuject syringe (NDC 00409-1893-01 )
15 mg/mL, 1 mL preservative-free Carpuject syringe (NDC 00409-1894-01)
50 mg/mL, 50 mL vial (NDC 00409-1134-05)
5 mg/mL, 30 mL PCA vial (NDC 00409-6028-04)
Morphine injection, West-Ward
5 mg/mL, 1 mL vial (NDC 00641-6073-25)
8 mg/mL, 1 mL vial (NDC 00641-6075-25)
10 mg/mL, 10 mL vial (NDC 00641-6068-01)
10 mg/mL, 1 mL vial (NDC 00641-6070-25)
15 mg/mL, 1 mL vial (NDC 00641-6071-25)
15 mg/mL, 20 mL vial (NDC 00641-6072-01)
Duramorph (preservative-free), West-Ward
1 mg/mL, 10 mL ampules (NDC 00641-6019-10)
Estimated Resupply Dates
- APP has all preservative-free Astramorph presentations on long-term back order and the company cannot estimate a release date.
- Hospira has several morphine injection presentations on back order. Morphine 25 mg/mL 4 mL Add-vantage vials and 1 mL preservative free vials have an estimated release date of May 2013. Morphine 0.5 mg/mL and 1 mg/mL preservative free vials have an estimated release date of mid-May 2013. Morphine 1 mg/mL 30 mL PCA vials are available in limited quantities. Morphine 50 mg/mL 20 mL vials have an estimated release date of late-May 2013. Morphine 25 mg/mL 10 mL Add-vantage vials have an estimated release date of June 2013.
- West-Ward has Infumorph 10 mg/mL and 25 mg/mL 20 mL ampules on back order and the company estimates a release date of June 2013.
- West-Ward has Duramorph 0.5 mg/mL 10 mL ampules on back order and the company estimates a release date of May 2013.
Related Shortages
Updated
April 25, 2013; April 9, 2013; April 1, 2013; March 21, 2013; March 5, 2013; February 6, 2013; January 23, 2013; January 15, 2013; January 9, 2013; December 12, 2012; November 30, 2012; November 9, 2012; October 24, 2012; October 1, 2012; September 18, 2012; September 4, 2012; August 31, 2012; August 9, 2012; June 15, 2012; May 25, 2012; May 21, 2012; April 20, 2012; April 4, 2012; March 21, 2012; March 7, 2012; February 23, 2012; February 7, 2012; January 24, 2012; January 13, 2012; December 22, 2011; December 6, 2011; November 21, 2011; November 4, 2011; October 19, 2011; October 11, 2011; September 29, 2011; September 1, 2011; August 19, 2011; July 28, 2011; July 14, 2011; June 23, 2011; May 5, 2011; March 24, 2011; February 15, 2011; January 6, 2011, University of Utah, Drug Information Service. Copyright 2013, Drug Information Service, University of Utah, Salt Lake City, UT.
Disclaimer
This information is provided through the support of Novation to ASHP solely as a service to its members, which shall not use this information for their further commercial use. The content was prepared by the Drug Information Center of University of Utah. Novation, ASHP, and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, which respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither Novation, ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this bulletin. Neither Novation, ASHP nor University of Utah endorses or recommends the use of any drug.
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