Dr. Denham is an international leader in patient safety and high-performance care solutions. He has taught and led research in medicine, engineering, and business leadership. He is involved in coordinating U.S. and international quality, certifying, and purchasing organizations along a path of harmonization of measures, standards, and practices, which encourages hospitals and healthcare organizations to dramatically improve patient safety and care performance. He co-chairs the U.S.-based National Quality Forum group that annually updates the NQF-Endorsed® Safe Practices for Better Healthcare, which are increasingly being tied to value-based purchasing. He chairs the Leapfrog Group Safe Practices Program, which influences more than $69 billion in purchasing power. He is Chairman of TMIT, which operates a National Research Test Bed of more than 3,100 hospitals, through which it pursues its mission of "saving lives, saving money, and building value in the communities served." Dr. Denham is a Senior Fellow of the Harvard Advanced Leadership Initiative, has a faculty appointment at the Harvard School of Public Health, and is an Adjunct Professor at the Mayo Clinic College of Medicine in Healthcare Engineering. He is the Editor-in-Chief of the Journal of Patient Safety and a co-founder of the Global Patient Safety Forum.