Products Affected - Description
Diuril oral suspension, Valeant
250 mg / 5 mL 237 mL bottle (NDC 65649-0311-12)
Reason for the Shortage
- Valeant cannot provide a reason for the shortage.1
- Valeant recently acquired Diuril oral suspension from Salix.1
There are no presentations available.
Estimated Resupply Dates
Valeant has Diuril oral suspension on back order and the company estimates a release date of early-September 2015.1
Implications for Patient Care
Chlorothiazide is a thiazide diuretic frequently used in pediatric patients to manage hypertension or for diuresis.2
Extemporaneously compounded chlorothiazide suspension may be a potential alternative during this shortage. Ensure appropriate compounding technique.
Alternative Agents & Management
Two publications are available outlining methods for compounding chlorothiazide 50 mg/mL oral suspension.3,4
- Valeant. Customer Service (personal communications). May 8, June 8, and August 10, 2015.
- McEvoy GK, Snow EK, Kester L, Litvak K, Miller J, Welsh OH, eds. AHFS DI (Lexi-Comp Online). Bethesda, MD: American Society of Health-System Pharmacists; 2015.
- Allen et al. Chlorothiazide 50 mg/mL oral suspension. International Journal of Pharmaceutical Compounding. 2014;18(4):326.
- Chlorothiazide. In: Nahata MC, Pai VB, eds. Pediatric Drug Formulations, 6th edition. Cincinnati, OH: Harvey Whitney Books Company; 2011.
Updated August 11, 2015 by Michelle Wheeler, PharmD, Drug Information Specialist. Created May 8, 2015 by Erin R. Fox, PharmD, Director, Drug Information Service. Copyright 2015, Drug Information Service, University of Utah, Salt Lake City, UT.
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