Multiple Vitamins for Infusion

[06 April 2016]

Products Affected - Description

Multivitamin for infusion (MVI) Adult, Hospira
MVI Adult, 10 mL two-chambered vials, 10 count (NDC 61703-0422-81)
MVI Adult, 2 x 5 mL Dual vial, 10 count (NDC 61703-0422-82)
MVI Adult, 2 x 50 mL Dual vial, 10 count (NDC 61703-0422-83)
Multivitamin for infusion (MVI) without Vitamin K Adult, Hospira
MVI-12 Adult, 50 mL Dual vial, 10 count (NDC 61703-0423-83)

Reason for the Shortage

  • Hospira states the shortage is due to manufacturing delays.
  • Baxter has all presentations fully available at this time.

Available Products

Infuvite for infusion, Baxter
Adult 2 x 5 mL single dose vials, 100 count (NDC 54643-5649-01)
Adult 2 x 50 mL bulk vials, 10 count (NDC 54643-5650-02)
Pediatric 5 mL single dose vials, 100 count (NDC 54643-5646-01)
Pediatric 50 mL bulk vials, single count (NDC 54643-5647-00)
Multivitamin for infusion (MVI) Pediatric lyophilized powder for solution for injection, Hospira
MVI Pediatric, lyophilized powder, 5 mL (once reconstituted) vials, 10 count (NDC 61703-0421-53)

Estimated Resupply Dates

Hospira has MVI Adult 10 mL two-chambered vials, MVI-12 without vitamin K 50 mL Dual vials, and MVI Adult 50 mL Dual vials on back order and the company cannot estimate a release date. The MVI Adult 5 mL Dual vials are on back order and the company estimates a release date of mid-June 2016.

Alternative Agents & Management

  • The American Society for Parenteral and Enteral Nutrition (ASPEN) has detailed recommendations for managing an intravenous multivitamin shortage in adults and pediatric patients online.
  • Key recommendations include:
    • Use oral or enteral multivitamin preparations whenever possible.
    • Use of pediatric intravenous multivitamins for adults is not recommended and may result in a shortage of pediatric products.
    • Use of multivitamin preparations without vitamin K is fine with individual supplementation of Vitamin K products. Ensure patients receiving vitamin K are getting adequate anticoagulation if they are on warfarin.
    • Reserve intravenous multivitamins for patients receiving parenteral nutrition.
    • Reserve pediatric intravenous multivitamins for children less than 2.5 kg or less than 36 weeks gestational age.
    • When all supply options are exhausted, ration intravenous multivitamins in parenteral nutrition or administer individual parenteral vitamins.
    • Purchase only the supply needed, do not stockpile.

Related Shortages


April 6, January 26, 2016; August 4, June 16, March 31, 13 and 4, January 23 and 8, 2015; November 14, October 15, August 26, July 25 and 9, June 25, May 1, March 20, January 9, 2014; October 7, August 21 and 5, June 18, May 3, April 15, February 26, January 30, 2013; December 12, October 10, September 5, August 9, July 18, June 4, May 16, April 13, March 9, February 24, January 18 and 3, 2012; December 13, November 15, October 31 and 11, September 14, August 1, July 14, June 28, 18, 7, 4, 3 and 1, March 30 and 28, February 4, 2011; December 2, September 29, August 4, July 16 and 2, May 19, April 13, March 1, February 2, January 11 and 8, 2010; November 17, September 11, 2009; November 17, October 22, September 26 and 9, August 25 and 11, July 28, 14 and 3, June 23, 2008, University of Utah, Drug Information Service. Copyright 2016, Drug Information Service, University of Utah, Salt Lake City, UT.


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