Multiple Vitamins for Infusion

[25 January 2017]

Products Affected - Description

Multivitamin for infusion (MVI) Pediatric lyophilized powder for solution for injection, Pfizer
MVI Pediatric, 5 mL vial, 10 count (NDC 61703-0421-53)
Multivitamin for infusion (MVI) Adult, Pfizer
MVI Adult, 10 mL two-chambered vial, 10 count (NDC 61703-0422-81) - discontinued
MVI Adult, 2 x 5 mL Dual vial, 10 count, NDC 61703-0422-82
MVI Adult, 2 x 50 mL Dual vial, 10 count, NDC 61703-0422-83

Multivitamin for infusion (MVI) without Vitamin K Adult, Pfizer
MVI-12 Adult, 50 mL Dual vial, 10 count (NDC 61703-0423-83) - discontinued

Reason for the Shortage

  • Hospira states the shortage is due to manufacturing delays.
  • Baxter has all presentations fully available at this time.

Available Products

Infuvite for infusion, Baxter
Adult 2 x 5 mL single dose vials, 100 count (NDC 54643-5649-01)
Adult 2 x 50 mL bulk vials, 10 count (NDC 54643-5650-02)
Pediatric 5 mL single dose vials, 100 count (NDC 54643-5646-01)
Pediatric 50 mL bulk vials, single count (NDC 54643-5647-00)

Estimated Resupply Dates

  • Hospira has MVI Adult 5 mL Dual vials and MVI Adult 50 mL Dual vials are on back order and the company estimates a release date of 1st quarter 2017.
  • Hospira has MVI pediatric 5 mL vials on back order and the company estimates a release date in 2nd quarter 2017.

Alternative Agents & Management

  • The American Society for Parenteral and Enteral Nutrition (ASPEN) has detailed recommendations for managing an intravenous multivitamin shortage in adults and pediatric patients online.
  • Key recommendations include:
    • Use oral or enteral multivitamin preparations whenever possible.
    • Use of pediatric intravenous multivitamins for adults is not recommended and may result in a shortage of pediatric products.
    • Use of multivitamin preparations without vitamin K is fine with individual supplementation of Vitamin K products. Ensure patients receiving vitamin K are getting adequate anticoagulation if they are on warfarin.
    • Reserve intravenous multivitamins for patients receiving parenteral nutrition.
    • Reserve pediatric intravenous multivitamins for children less than 2.5 kg or less than 36 weeks gestational age.
    • When all supply options are exhausted, ration intravenous multivitamins in parenteral nutrition or administer individual parenteral vitamins.
    • Purchase only the supply needed, do not stockpile.

Related Shortages


January 25, 2017; December 12, November 7, October 5, September 7, August 16 and 1, July 14 and 7, June 22, April 6, January 26, 2016; August 4, June 16, March 31, 13 and 4, January 23, 2015; November 14, October 15, August 26, July 25, June 25, May 1, March 20, January 9, 2014; October 7, August 21, June 18, May 3, April 15, February 26, January 30, 2013; December 12, October 10, September 5, August 9, July 18, June 4, May 16, April 13, March 9, February 24, January 18, 2012; December 13, November 15, October 31, September 14, August 1, July 14, June 28, March 30, February 4, 2011; December 2, September 29, August 4, July 16 and 2, May 19, April 13, March 1, February 2, January 11, 2010; November 17, September 11, 2009; November 17, October 22, September 26, August 25, July 28, June 23, 2008, University of Utah, Drug Information Service. Copyright 2016, Drug Information Service, University of Utah, Salt Lake City, UT.


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