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Multiple Vitamins for Infusion

[14 November 2014]

Products Affected - Description

Multivitamin for infusion (MVI) Adult, Hospira
MVI Adult, 10 mL two-chambered vials (NDC 61703-0422-81)
MVI Adult, 2 x 5 mL Dual vials (NDC 61703-0422-82)
MVI Adult, 2 x 50 mL Dual vials (NDC 61703-0422-83)

Multivitamin for infusion (MVI) Without Vitamin K Adult, Hospira
MVI-12 Adult, 50 mL Dual vials (NDC 61703-0423-83)
 
Infuvite for infusion, Baxter
Adult 2 x 50 mL bulk vials (NDC 54643-5650-02)

Reason for the Shortage

  • Hospira states the shortage is due to manufacturing delays.
  • Baxter states the reason for the shortage was manufacturing delays.

Available Products

Infuvite for infusion, Baxter
Adult 2 x 5 mL single dose vials (NDC 54643-5649-01)
Pediatric 5 mL single dose vials (NDC 54643-5646-01)
Pediatric 50 mL bulk vials (NDC 54643-5647-00)
 
Multivitamin for infusion (MVI) Pediatric, Hospira
MVI Pediatric, lyophilized powder, 5 mL (once reconstituted) vials (NDC 61703-0421-53)

Estimated Resupply Dates

  • Hospira has all adult multivitamin for infusion on back order and cannot estimate a release date.
  • Baxter has Infuvite adult 2 x 50 mL vials available but is reviewing orders prior to release.

Alternative Agents & Management

  • The American Society for Parenteral and Enteral Nutrition (ASPEN) has detailed recommendations for managing an intravenous multivitamin shortage in adults and pediatric patients online.
  • Key recommendations include:
    • Use oral or enteral multivitamin preparations whenever possible.
    • Use of pediatric intravenous multivitamins for adults is not recommended and may result in a shortage of pediatric products.
    • Use of multivitamin preparations without vitamin K is fine with individual supplementation of Vitamin K products. Ensure patients receiving vitamin K are getting adequate anticoagulation if they are on warfarin.
    • Reserve intravenous multivitamins for patients receiving parenteral nutrition.
    • Reserve pediatric intravenous multivitamins for children less than 2.5 kg or less than 36 weeks gestational age.
    • When all supply options are exhausted, ration intravenous multivitamins in parenteral nutrition or administer individual parenteral vitamins.
    • Purchase only the supply needed, do not stockpile.

Related Shortages

Updated

November 14, 2014; October 15, 2014; August 26, 2014; July 25, 2014; July 9, 2014; June 25, 2014; May 1, 2014; March 20, 2014; January 9, 2014; October 7, 2013; August 21, 2013; June 18, 2013; May 3, 2013; April 15, 2013; February 26, 2013; January 30, 2013; December 12, 2012; October 10, 2012; September 10, 2012; August 9, 2012; July 18, 2012; May 24, 2012; April 13, 2012; March 9, 2012; February 24, 2012; January 18, 2012; January 3, 2012; December 13, 2011; November 15, 2011; October 31, 2011; September 14, 2011; August 1, 2011; July 14, 2011; June 28, 2011; April 18, 2011; March 28, 2011, February 4, 2011; December 2, 2010; September 29, 2010; August 4, 2010; July 16, 2010; July 2, 2010; May 19, 2010; April 13, 2010; March 1, 2010; February 2, 2010; January 11, 2010; January 8, 2010; November 17, 2009; September 11, 2009, University of Utah, Drug Information Service. Copyright 2014, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

This information is provided through the support of Novation to ASHP solely as a service to its members, which shall not use this information for their further commercial use. The content was prepared by the Drug Information Center of University of Utah. Novation, ASHP, and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, which respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither Novation, ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this bulletin. Neither Novation, ASHP nor University of Utah endorses or recommends the use of any drug.

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