Caffeine Citrate Injection and Oral Solution

[22 July 2014]

Products Affected - Description

Caffeine citrate injection
Caffeine citrate injection, American Regent
20 mg/mL, 3 mL vial (NDC 00517-0020-10)
Cafcit injection, Bedford
20 mg/mL, 3 mL vial (NDC 55390-0357-03) - discontinued

Caffeine citrate injection, Fresenius Kabi
20 mg/mL, 3 mL vial (NDC 63323-0407-03)
Caffeine citrate injection, Paddock
20 mg/mL, 3 mL vial (NDC 00574-0823-01) - discontinued
Caffeine citrate injection, Sagent
20 mg/mL, 3 mL vial (NDC 25021-0601-03)
Cafcit injection, West-Ward
20 mg/mL, 3 mL vial (NDC 55390-0357-03)

Caffeine citrate oral solution
Cafcit oral solution, Bedford
20 mg/mL oral solution, 3 mL vial (NDC 55390-0358-03) - discontinued

Caffeine citrate oral solution, Paddock
20 mg/mL oral solution, 3 mL vial (NDC 00574-0152-10) - discontinued

Reason for the Shortage

  • American Regent had temporarily suspended manufacture of most drug products in April, 2011.
  • American Regent resumed manufacturing in Shirley, New York in early-May, 2011.
  • Paddock discontinued caffeine citrate injection and oral solution in May 2014.
  • Sagent states the reason for the shortage is increased demand.
  • West-Ward Pharmaceuticals’ parent company, Hikma Pharmaceuticals, acquired Cafcit injection from Bedford in July 2014. West-Ward will actively market Cafcit injection.

Available Products

Caffeine citrate injection
Caffeine citrate injection, Caraco
20 mg/mL, 3 mL vial (NDC 47335-0289-40)

Caffeine citrate oral solution

Caffeine citrate oral solution, Fresenius Kabi
20 mg/mL oral solution, 3 mL vial (NDC 63323-0406-03)
Caffeine citrate oral solution, Caraco
20 mg/mL oral solution, 3 mL vial (NDC 47335-0290-44)
Caffeine citrate oral solution, Sagent
20 mg/mL, 3 mL vial (NDC 25021-0602-03)

Estimated Resupply Dates

Caffeine citrate injection
  • American Regent has caffeine citrate 20 mg/mL 3 mL vials for injection on back order and the company cannot estimate a release date.
  • Fresenius Kabi has caffeine citrate 3 mL vials on back order and the company estimates a release date in mid-August 2014.
  • Sagent has caffeine citrate 3 mL vials on back order and the company estimates a release date in August 2014.
  • West-Ward estimates Cafcit injection will be available for ordering and shipping starting in late-July 2014.

Caffeine citrate oral solution

  • All presentations are currently available.

Related Shortages


July 22, 2014; June 30, 2014; May 15, 2014; May 14, 2014; May 5, 2014; April 21, 2014; April 3, 2014; February 27, 2014; February 3, 2014; December 13, 2013; November 4, 2013; September 12, 2013; August 28, 2013; August 22, 2013; July 18, 2013; June 27, 2013; May 20, 2013; May 15, 2013; March 7, 2013; December 19, 2012; October 18, 2012; September 24, 2012; July 12, 2012; May 25, 2012; April 17, 2012; March 20, 2012; March 9, 2012; February 7, 2012; January 3, 2012; December 21, 2011; November 30, 2011; November 21, 2011; November 11, 2011, University of Utah, Drug Information Service. Copyright 2014, Drug Information Service, University of Utah, Salt Lake City, UT.


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