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Bupivacaine with epinephrine Injection

[26 February 2015]

Products Affected - Description

Bupivacaine 0.25% with epinephrine
No presentations are affected.

Bupivacaine 0.5% with epinephrine
Sensorcaine 0.5% with epinephrine 1:200,000, Fresenius Kabi
10 mL vial, preservative-free (NDC 63323-0462-17)
50 mL vial, multi-dose (NDC 63323-0463-57)
 
Bupivacaine 0.75% with epinephrine
No presentations are affected.

Reason for the Shortage

  • Fresenius Kabi (formerly APP) has Sensorcaine with epinephrine on shortage due to increased demand for the product.
  • Hospira had bupivacaine with epinephrine on shortage due to manufacturing delays.

Available Products

Bupivacaine 0.25% with epinephrine
Bupivacaine 0.25% with epinephrine 1:200,000 injection, Hospira
10 mL vial, preservative-free (NDC 00409-9042-01)
30 mL vial, preservative-free (NDC 00409-9042-17)
50 mL vial, multi-dose (NDC 00409-9043-01)
 
Marcaine 0.25% (with epinephrine 1:200,000) injection, Hospira
10 mL vial, preservative-free (NDC 00409-1746-10)
30 mL vial, preservative-free (NDC 00409-1746-30)
50 mL vial, multi-dose (NDC 00409-1752-50)
 
Sensorcaine 0.25% (with epinephrine 1:200,000), Fresenius Kabi
10 mL vial, preservative-free (NDC 63323-0468-17)
30 mL vial, preservative-free (NDC 63323-0468-37)
50 mL vial, multi-dose (NDC 63323-0461-57)

Bupivacaine 0.5% with epinephrine
Sensorcaine 0.5% with epinephrine 1:200,000, Fresenius Kabi
30 mL vial, preservative-free, sterile pack (NDC 63323-0462-31)
30 mL vial, preservative-free (NDC 63323-0462-37)

Bupivacaine 0.5% with epinephrine 1:200,000 injection, Hospira
10 mL vial, preservative-free (NDC 00409-9045-01)
30 mL vial, preservative-free (NDC 00409-9045-17)
50 mL vial, multi-dose (NDC 00409-9046-01)

Marcaine 0.5% with epinephrine 1:200,000 injection, Hospira
10 mL vial, preservative-free (NDC 00409-1749-10)
30 mL vial, preservative-free (NDC 00409-1749-29)
50 mL vial, multi-dose (NDC 00409-1755-50)

Bupivacaine 0.75% with epinephrine
Sensorcaine 0.75% with epinephrine 1:200,000, Fresenius Kabi
30 mL vial, preservative-free (NDC 63323-0460-37)

Estimated Resupply Dates

Bupivacaine 0.25% with epinephrine
  • All presentations are available.

Bupivacaine 0.5% with epinephrine

  • Fresenius Kabi has Sensorcaine 0.5% with epinephrine 50 mL vials on back order and the company estimates a release date of early-March 2015. Sensorcaine 0.5% with epinephrine 10 mL preservative-free vials are available with an expiration date of <9 months.

Bupivacaine 0.75% with epinephrine

  • All presentations are available.

Related Shortages

Updated

February 3 and 26, 2015; December 2, November 14, October 2 and 14, September 8 and 10, August 6 and 29, July 16, June 2, 11, and 26, May 1 and 12, April 16, March 6, 14, and 27, February 7 and 27, January 3, 14, and 21, 2014; December 3, 13, and 27, November 5 and 19, October 7, September 18 and 25, August 5, 13, and 28, July 12, June 24, May 22, April 29, March 5 and 29, February 22, January 2 and 28, 2013; January 2, 2013; December 18, November 9 and 28, October 8 and 22, September 24, August 22, July 25, June 5 and 28, May 17, April 16, March 7 and 27, February 8 and 22, January 5 and 25, 2012; December 7 and 21, November 16, October 12, 27, and 31, September 21, August 24, July 13 and 28, June 1, 23, and 30, May 23, April 7 and 28, March 10, 15, and 24, February 4, January 10, 21, and 25, 2011; December 6 and 20, October 19, 2010, University of Utah, Drug Information Service. Copyright 2015, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

This information is provided through the support of Novation to ASHP solely as a service to its members, which shall not use this information for their further commercial use. The content was prepared by the Drug Information Center of University of Utah. Novation, ASHP, and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, which respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither Novation, ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this bulletin. Neither Novation, ASHP nor University of Utah endorses or recommends the use of any drug.

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