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Bupivacaine with epinephrine Injection

[21 February 2017]

Products Affected - Description

Bupivacaine (with epinephrine 1:200,000) injection, Pfizer
0.25%, 10 mL vial, 50 count (NDC 00409-9042-01)
0.25%, 30 mL vial, 100 count (NDC 00409-9042-17)
0.25%, 50 mL vial, 25 count (NDC 00409-9043-01)
0.5%, 10 mL vial, 50 count (NDC 00409-9045-01)
0.5%, 30 mL vial, 100 count (NDC 00409-9045-17)
 
Marcaine (with epinephrine 1:200,000) injection, Pfizer
0.25%, 10 mL vial, 10 count (NDC 00409-1746-10)
0.25%, 50 mL vial, 1 count (NDC 00409-1752-50)
0.5%, 10 mL vial, 10 count (NDC 00409-1749-10)
0.5%, 50 mL vial, 1 count (NDC 00409-1755-50)
 
Sensorcaine (with epinephrine 1:200,000) injection, Fresenius Kabi
0.25%, 50 mL vial, 25 count (NDC 63323-0461-57)
0.5%, 50 mL vial, 25 count (NDC 63323-0463-57)
 
Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi
0.25%, 10 mL vial, 25 count (NDC 63323-0468-17)
0.5%, 10 mL vial, 25 count (NDC 63323-0462-17)
0.5%, 30 mL sterile pack vial, 5 count (NDC 63323-0462-31)
0.5%, 30 mL vial, 25 count (NDC 63323-0462-37)

Reason for the Shortage

  • Fresenius Kabi has bupivacaine and epinephrine on shortage due to increased demand and manufacturing delays.
  • Pfizer has bupivacaine with epinephrine on shortage due to manufacturing delays.

Available Products

Bupivacaine (with epinephrine 1:200,000) injection, Pfizer
0.5%, 50 mL vial, 25 count (NDC 00409-9046-01)
 
Marcaine (with epinephrine 1:200,000) injection, Pfizer
0.25%, 30 mL vial, 10 count (NDC 00409-1746-30)
0.5%, 30 mL vial, 10 count (NDC 00409-1749-29)
 
Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi
0.25%, 30 mL vial, 25 count (NDC 63323-0468-37)
0.75%, 30 mL vial, 25 count (NDC 63323-0460-37)

Estimated Resupply Dates

  • Fresenius Kabi has 0.25% Sensorcaine-MPF with epinephrine 10 mL vials and 0.5% Sensorcaine-MPF with epinephrine 10 mL vials on back order and the company estimates a release date of mid-April 2017. The 0.25% Sensorcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of late-February 2017. The 0.5% Sensorcaine-MPF with epinephrine 30 mL vials are on back order and the company estimates a release date of late-March 2017. The 0.5% Sensorcaine-MPF with epinephrine 30 mL vials sterile packs are on back order and the company estimates a release date of mid-April 2017. The 0.5% Sensorcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of late-February 2017.
  • Pfizer has 0.25% bupivacaine with epinephrine 10 mL and 30 mL preservative-free vials available in limited supply. The 0.25% bupivacaine with epinephrine 50 mL vials are available in limited supply. The 0.5% bupivacaine with epinephrine 10 mL and 30 mL preservative-free vials are available in limited supply.
  • Pfizer has 0.25% Marcaine with epinephrine 10 mL preservative-free vials available in limited supply. The 0.25% Marcaine 50 mL vials are on back order and the company estimates a release date of late-February 2017. The 0.5% Marcaine with epinephrine 10 mL preservative-free vials are available in limited supply. The 0.5% Marcaine 50 mL vials are on back order and the company estimates a release date of late-February 2017.

Related Shortages

Updated

February 21, 16 and 7, January 26 and 13, 2017; December 19 and 2, November 21, 11 and 7, October 19, September 27, 13 and 2, 2016, University of Utah, Drug Information Service. Copyright 2017, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

This information is provided through the support of Vizient to ASHP solely as a service to its members, which shall not use this information for their further commercial use. The content was prepared by the Drug Information Center of University of Utah. Vizient, ASHP, and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, which respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither Vizient, ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this bulletin. Neither Vizient, ASHP nor University of Utah endorses or recommends the use of any drug.

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