Chromium (Chromic Chloride) Injection

[07 October 2014]

Products Affected - Description

Chromic chloride injection, American Regent
4 mcg/mL 10 mL vial, 25 count (NDC 00517-6310-25)

Reason for the Shortage

American Regent has chromic chloride injection on shortage due to manufacturing delays.

Available Products

Chromium (chromic chloride) injection, Hospira
4 mcg/mL 10 mL vial, 25 count (NDC 00409-4093-01)

Estimated Resupply Dates

  • American Regent has chromium (chromic chloride) injection on back order and the company cannot estimate a release date.
  • Hospira has been supplying the market for several months.

Alternative Agents & Management

The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) has detailed recommendations for managing this shortage online.
Key recommendations include:
  • There is no need to supplement chromium (chromic chloride) during a shortage except in patients showing signs of clinical deficiency (eg, glucose intolerance, hyperlipidemia, peripheral neuropathy, and encephalopathy).
  • Consider oral or enteral multi-vitamin or multi-mineral products for supplementation if possible.
  • Reserve supplies for neonatal or pediatric patients or other vulnerable groups such as patients with short bowel or malabsorption syndromes.
  • Avoid using trace elements additives in IV fluids.
  • Increase vigilance of signs and symptoms of trace element deficiencies.
  • Purchase only the supply needed, do not stockpile.

Related Shortages


October 7, 2014; September 29, 2014; July 8, 2014; April 25, 2014; February 10, 2014; December 27, 2013; December 13, 2013; November 25, 2013; November 1, 2013; October 15, 2013; September 26, 2013; September 19, 2013; August 29, 2013; August 16, 2013; June 24, 2013; May 30, 2013; May 3, 2013; April 1, 2013; February 22, 2013; January 23, 2013; December 31, 2012; December 10, 2012; October 19, 2012; August 7, 2012; May 24, 2012; April 11, 2012; March 5, 2012; January 3, 2012; November 21, 2011, University of Utah, Drug Information Service. Copyright 2014, Drug Information Service, University of Utah, Salt Lake City, UT.


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