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Mineral Oil and Petrolatum Ophthalmic Ointment

Products Affected - Description

    • Artificial Tears, Rugby Laboratories, 15%/83%, 3.5 g NDC 00536-1086-91 - discontinued
    • Genteal PM Ointment, Alcon Labs, 15%/85%, 3.5 g Product 00078-0473-97
    • Lubrifresh PM, Major, 15%/83%, 3.5 g NDC 00904-6488-38
    • Puralube, Perrigo, 15%/85%, 1 g 20 count, NDC 00574-4025-20 - discontinued
    • Puralube, Perrigo, 15%/85%, 3.5 g NDC 00574-4025-35 - discontinued
    • Refresh Lacri-Lube, Allergan, 42.5%/56.8%, 3.5 g NDC 00023-0312-04
    • Refresh Lacri-Lube PM, Allergan, 42.5%/56.8%, 7 g NDC 00023-0312-07
    • Systane Nighttime Ointment, Alcon Labs, 3%/94%, 3.5 g Product 00065-0509-35

Reason for the Shortage

    • Allergan states the shortage is due to production delays.
    • Bausch Health has Soothe Night Time ointment available.
    • Major did not provide a reason for the shortage.
    • Alcon states the shortage is due to manufacturing issues.
    • Perrigo discontinued Puralube ointment products in early-2019.
    • Rugby discontinued Artificial Tears 3.5 gram tubes in January 2019.

Available Products

    • Refresh PM, Allergan, 42.5%/57.3%, 3.5 g NDC 00023-0240-04
    • Soothe Night Time, Bausch Health, 20%/80%, 3.5 g NDC 10119-0223-99

Estimated Resupply Dates

    • Alcon has Systane Nighttime ointment and Genteal PM ointment on back order and the company estimates a release date in late-July 2019.
    • Allergan has Lacri-Lube SOP ointment 3.5 gram, and Lacri-Lube SOP ointment 7 gram tubes on back order and the company estimates a release date in late-July 2019.
    • Major has Lubrifresh PM 3.5 gram tubes on back order and the company estimates a release date of October 2019.


Updated July 10, 2019 by Megan Dryer, PharmD. Created June 6, 2018 by Anthony Trovato, PharmD, BCPS. © 2019, Drug Information Service, University of Utah, Salt Lake City, UT.


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