4/7/2024

Bupivacaine with Epinephrine Injection

Products Affected - Description

- Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 10 mL vial, 50 count, NDC 00409-9042-01
- Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 30 mL vial, 100 count, NDC 00409-9042-17
- Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 50 mL vial, 25 count, NDC 00409-9043-01
- Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 10 mL vial, 50 count, NDC 00409-9045-01
- Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 30 mL vial, 100 count, NDC 00409-9045-17
- Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 50 mL vial, 25 count, NDC 00409-9046-01
- Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 10 mL vial, 10 count, NDC 00409-1746-10
- Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 30 mL vial, 10 count, NDC 00409-1746-30
- Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 50 mL vial, 1 count, NDC 00409-1752-50
- Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 10 mL vial, 10 count, NDC 00409-1749-10
- Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 30 mL vial, 10 count, NDC 00409-1749-29
- Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 50 mL vial, 1 count, NDC 00409-1755-50
- Sensorcaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.25%, 50 mL vial, 25 count, NDC 63323-0461-57
- Sensorcaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 50 mL vial, 25 count, NDC 63323-0463-57
- Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.25%, 10 mL vial, 25 count, NDC 63323-0468-17
- Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.25%, 30 mL vial, 25 count, NDC 63323-0468-37
- Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 10 mL vial, 25 count, NDC 63323-0462-17
- Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 30 mL sterile pack vial, 5 count, NDC 63323-0462-31
- Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 30 mL vial, 25 count, NDC 63323-0462-37
- Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.75%, 30 mL vial, 25 count, NDC 63323-0460-37

Reason for the Shortage

- Fresenius Kabi has bupivacaine and epinephrine on shortage due to increased demand.
- Pfizer has bupivacaine with epinephrine on shortage due to manufacturing delays.

Available Products

- There are no presentations available

Estimated Resupply Dates

- Fresenius Kabi has 0.25% Sensorcaine-MPF with epinephrine 10 mL and 30 mL vials on back order and the company estimates a release date of 3rd quarter 2024. The 0.25% Sensorcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of 3rd quarter 2024. The 0.5% Sensorcaine-MPF with epinephrine 10 mL and 30 mL vials are on back order and the company estimates a release date of 3rd quarter 2024. The 0.5% Sensorcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of 3rd quarter 2024. The 0.5% Sensorcaine-MPF with epinephrine 30 mL sterile packs are on back order and the company estimates a release date of 3rd quarter 2024. The 0.75% Sensorcaine-MPF with epinephrine 30 mL vials are on back order and the company estimates a release date of 3rd quarter 2024.
- Pfizer has 0.25% bupivacaine with epinephrine 10 mL and 30 mL preservative-free vials on back order and the company estimates a release date of June 2025. The 0.25% bupivacaine with epinephrine 50 mL vials are on back order and the company estimates a release date of June 2025. The 0.5% bupivacaine with epinephrine 10 mL and 30 mL preservative-free vials are on back order and the company estimates a release date of June 2025. The 0.5% bupivacaine with epinephrine 50 mL vials are on back order and the company estimates a release date of April 2025.
- Pfizer has 0.25% Marcaine with epinephrine 10 mL vials available via direct orders only. The 0.25% Marcaine with epinephrine 30 mL vials and 50 mL vials are available in limited supply. The 0.5% Marcaine with epinephrine 10 mL vials are available in limited supply. The 0.5% Marcaine with epinephrine 30 mL vials and 50 mL vials are on back order and the company estimates a release date of May 2024. All Marcaine with epinephrine presentations are only available via direct orders.

Updated

Updated April 7, 2024 by Michelle Wheeler, PharmD, Drug Information Specialist. Created September 2, 2016 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2024, Drug Information Service, University of Utah, Salt Lake City, UT.

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