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9/6/2019

Multiple Vitamins for Infusion

Products Affected - Description

    • Multivitamin for infusion (MVI) Adult, Pfizer, MVI Adult, 2 x 5 mL Dual vial, 1 count, NDC 61703-0434-82
    • Multivitamin for infusion (MVI) Adult, Pfizer, MVI Adult, 2 x 50 mL Dual vial, 10 count, NDC 61703-0422-83
    • Multivitamin for infusion (MVI) Pediatric lyophilized powder for solution for injection, Pfizer, MVI Pediatric, 5 mL vial, 10 count, NDC 61703-0421-53

Reason for the Shortage

    • Pfizer states the shortage is due to manufacturing delays.
    • Baxter has all presentations fully available at this time.

Available Products

    • Infuvite injection, Baxter, Adult, 2 x 5 mL single dose vial, 100 count, NDC 54643-5649-01
    • Infuvite injection, Baxter, Adult, 2 x 50 mL bulk vial, 10 count, NDC 54643-5650-02
    • Infuvite injection, Baxter, Pediatric, 5 mL single dose vial, 100 count, NDC 54643-5646-01
    • Infuvite injection, Baxter, Pediatric, 50 mL bulk vial, 1 count, NDC 54643-5647-00

Estimated Resupply Dates

    • Pfizer has M.V.I. Adult 2 X 5 mL Dual vials, M.V.I. Adult 2 X 50 mL vials, and Pediatric 5 mL vials on back order and the company estimates a release date of September 2019 for the Adult 2 x 5 mL vials, November 2020 for the Adult 2 x 50 mL vials, and June 2020 for the Pediatric 5 mL vials.

Alternative Agents & Management

    • The American Society for Parenteral and Enteral Nutrition (ASPEN) has detailed recommendations for managing an intravenous multivitamin shortage in adults and pediatric patients, http://www.nutritioncare.org/lcontent.aspx?id=5346.
    • Key recommendations include:
    • Use oral or enteral multivitamin preparations whenever possible.
    • Use of pediatric intravenous multivitamins for adults is not recommended and may result in a shortage of pediatric products.
    • Use of multivitamin preparations without vitamin K is fine with individual supplementation of Vitamin K products. Ensure patients receiving vitamin K are getting adequate anticoagulation if they are on warfarin.
    • Reserve intravenous multivitamins for patients receiving parenteral nutrition.
    • Reserve pediatric intravenous multivitamins for children less than 2.5 kg or less than 36 weeks gestational age.
    • When all supply options are exhausted, ration intravenous multivitamins in parenteral nutrition or administer individual parenteral vitamins.
    • Purchase only the supply needed, do not stockpile.

Updated

Updated September 6, 2019 by Michelle Wheeler, PharmD, Drug Information Specialist. Created June 23, 2008 by Jane Chandramouli, PharmD, Drug Information Specialist. © 2019, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

This information is provided through the support of Vizient to ASHP solely as a service to its members, which shall not use this information for their further commercial use. The content was prepared by the Drug Information Center of University of Utah. Vizient, ASHP, and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, which respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither Vizient, ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this bulletin. Neither Vizient, ASHP nor University of Utah endorses or recommends the use of any drug.

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