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11/9/2016

70% Dextrose Injection Large Volume Bags

Products Affected - Description

    • 70% Dextrose injection, BBraun, 1000 mL glass bottle, 6 count, NDC 00264-1290-55

Reason for the Shortage

    • Baxter stated they had increased demand for the product.[1]
    • BBraun discontinued 70% dextrose in 1,000 mL glass bottles. The 70% dextrose 2,000 mL bags are available.[2]
    • Hospira had product on shortage due to increased demand.[3]

Available Products

    • 70% Dextrose injection, BBraun, 2000 mL bag, 4 count, NDC 00264-7387-50
    • 70% Dextrose injection, Baxter, 2000 mL bag, 6 count, NDC 00338-0719-06
    • 70% Dextrose injection, Pfizer, 2000 mL bag, 6 count, NDC 00409-7120-07
    • 70% Dextrose injection, Pfizer, 500 mL in 1000 mL partial fill bag, 12 count, NDC 00409-7918-19

Estimated Resupply Dates

    • All marketed presentations available.

Implications for Patient Care

    • Solutions of 70% dextrose are used to compound a variety items including specialized solutions for neonatal or pediatric patients and total parenteral nutrition (TPN).[4]

Safety

    • Clinicians must use care if using another strength of dextrose injection for compounding (such as 50% dextrose injection). Ensure compounding software is updated prior to using a different strength.

Alternative Agents & Management

    • Clinicians should reserve remaining supplies of 70% dextrose for their most critical patients.
    • Consider using premixed total parenteral nutrition solutions if appropriate.

References

    1. Baxter (personal communications). September 30, November 7, 2014; January 13 and 16, February 23, March 22, May 11, August 3 and 12, September 18, October 29, 2015; January 26, April 6, June 20, July 20, and November 8, 2016.
    2. BBraun (personal communications). September 30, November 7, 2014; May 11, August 3, September 17, October 30, 2015; January 26, April 4, June 2, and November 8, 2016.
    3. Hospira (personal communications and website). September 30, November 10, 2014; January 14, February 23, March 22, May 12, August 3, September 18, October 30, 2015; January 26, April 5, June 27, July 21, and November 8, 2016.
    4. Hospira. 50% and 70% Dextrose Injection, USP [product information]. Lake Forest, IL: Hospira; 2014.

Updated

Updated November 9, 2016 by Elyse MacDonald, PharmD, MS, BCPS. Created August 4, 2015 by Jane Chandramouli, PharmD, Drug Information Specialist. Copyright 2017, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

This information is provided through the support of Vizient to ASHP solely as a service to its members, which shall not use this information for their further commercial use. The content was prepared by the Drug Information Center of University of Utah. Vizient, ASHP, and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, which respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither Vizient, ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this bulletin. Neither Vizient, ASHP nor University of Utah endorses or recommends the use of any drug.

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