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5/20/2026

Nitrofurantoin Oral Suspension

Products Affected - Description

    • Furadantin oral suspension, Casper, 25 mg/5 mL, 230 mL bottle, NDC 70199-0006-32 - discontinued
    • Nitrofurantoin oral suspension, Amneal, 25 mg/5 mL, 230 mL bottle, UPC 65162-0689-88 - discontinued
    • Nitrofurantoin oral suspension, Lupin, 25 mg/5 mL, 230 mL bottle, UPC 43386-0450-11 - discontinued
    • Nitrofurantoin oral suspension, Nostrum, 25 mg/5 mL, 240 mL bottle, NDC 70408-0239-32 - discontinued
    • Nitrofurantoin oral suspension, Teva, 25 mg/5 mL, 230 mL bottle, NDC 00472-1992-08 - discontinued

Reason for the Shortage

    • Ani has nitrofurantoin oral suspension available.
    • Biocon has nitrofurantoin oral suspension available.
    • Casper Pharma discontinued Furadantin in April 2026.
    • Nostrum has ceased operations.
    • Rising has the authorized generic of nitrofurantoin oral suspension available.
    • Somerset has nitrofurantoin oral suspension available.
    • Teva discontinued nitrofurantoin oral suspension in the first half of 2026.

Available Products

    • Nitrofurantoin oral suspension, Ani Pharmaceuticals, 25 mg/5 mL, 230 mL bottle, NDC 70954-0496-10
    • Nitrofurantoin oral suspension, Biocon, 25 mg/5 mL, 230 mL bottle, NDC 70377-0118-31
    • Nitrofurantoin oral suspension, Rising Pharmaceuticals, 25 mg/5 mL, 230 mL bottle, NDC 64980-0593-24
    • Nitrofurantoin oral suspension, Rising Pharmaceuticals, 50 mg/5 mL, 60 mL bottle, NDC 16571-0888-06
    • Nitrofurantoin oral suspension, Somerset Therapeutics LLC, 25 mg/5 mL, 230 mL bottle, NDC 70069-0829-01

Alternative Agents & Management

    • Nitrofurantoin 2 mg/mL suspension can be made from nitrofurantoin bulk powder and SyrSpend SF PH4 vehicle. Mix nitrofurantoin with a small amount of suspending vehicle to form a paste. Dilute the paste with additional SyrSpendSF to a final volume of 300 mL. Store at room temperature or under refrigeration in light-resistant bottles. Suspension is stable for 90 days.[1]
    • Macrodantin (nitrofurantoin macrocrystalline) capsules can be opened and mixed with food or water and flushed down a tube.[2]
    • Macrobid (nitrofurantoin monohydrate/macrocrystalline) capsules should not be opened as this may interfere with the nitrofurantoin release mechanism.[2]

References

    1. De Oliveira, FA, Polonini HC, Loures da Silva S, et al., (2017). Stability of Alprazolam, Atropine Sulfate, Glutamine, Levofloxacin, Metoprolol Tartrate, Nitrofurantion, Ondansetron HCl, Oxandrolone, Pregabaline, and Riboflavin in SyrSpend SF PH4 Oral Suspensions. International Journal of Pharmaceutical Compounding, 21(3), 255-263.
    2. Alvogen Customer Service (personal communications). June 5, 2018.

Updated

Updated May 20, 2026 by Leslie Jensen, PharmD, Drug Information Specialist. Created June 5, 2018 by Leslie Jensen, PharmD, Drug Information Specialist. © 2026, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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