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Asparaginase Erwinia chrysanthemi

Reason for the Shortage

    • Jazz has Erwinaze available.

Available Products

    • Erwinaze, Jazz Pharmaceuticals, 10,000 unit, 3 mL vial, 5 count, NDC 57902-0249-05

Estimated Resupply Dates

    • Jazz Pharmaceuticals has Erwinaze available.


    • Jazz Pharmaceuticals sent Dear Health Care Provider letters regarding the administration of certain batches of Erwinaze (Batches 174K, 177K, 178K, 179K, 180K, 181K, 182K, 183K, 184K, 185ak, 186). Particulate matter was seen in vials from these batches during routine inspections. Jazz states that these batches must be given intramuscularly only and NOT intravenously. Batch 187K may be given either intramuscularly or intravenously via tubing with a 0.2-micron, low-protein-binding, in-line filter. Use 5-micron filter needles when withdrawing Erwinaze from vials. The most recent letter with further details can be found at and


Updated June 20, 2018 by Leslie Jensen, PharmD, Drug Information Specialist. Created October 11, 2016 by Elyse MacDonald, PharmD, MS, BCPS. Copyright 2018, Drug Information Service, University of Utah, Salt Lake City, UT.


Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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