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7/25/2022

Iopamidol Injection

Products Affected - Description

    • Isovue Multipack-250 solution for injection, Bracco Diagnostics, 51%, 200 mL bulk glass bottle, 10 count, NDC 00270-1317-41 - discontinued
    • Isovue Multipack-300 solution for injection, Bracco Diagnostics, 61%, 200 mL pharmacy bulk glass bottle, 10 count, NDC 00270-1315-41 - discontinued
    • Isovue Multipack-300 solution for injection, Bracco Diagnostics, 61%, 500 mL pharmacy bulk glass bottle, 6 count, NDC 00270-1315-98 - discontinued
    • Isovue Multipack-370 solution for injection, Bracco Diagnostics, 76%, 200 mL pharmacy bulk glass bottle, 10 count, NDC 00270-1316-41 - discontinued
    • Isovue Multipack-370 solution for injection, Bracco Diagnostics, 76%, 500 mL pharmacy bulk glass bottle, 6 count, NDC 00270-1316-98 - discontinued
    • Isovue-200 solution for injection, Bracco Diagnostics, 41%, 200 mL single dose glass bottle, 10 count, NDC 00270-1314-15
    • Isovue-200 solution for injection, Bracco Diagnostics, 41%, 50 mL single dose vial, 10 count, NDC 00270-1314-30 - discontinued
    • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 100 mL single dose glass bottle, 10 count, NDC 00270-1317-02
    • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 150 mL single dose glass bottle, 10 count, NDC 00270-1317-09 - discontinued
    • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 50 mL single dose vial, 10 count, NDC 00270-1317-05 - discontinued
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 100 mL single dose glass bottle, 10 count, NDC 00270-1315-35
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 150 mL single dose glass bottle, 10 count, NDC 00270-1315-50
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 200 mL imaging bulk package glass bottle, 10 count, NDC 00270-1315-45
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 30 mL single dose vial, 10 count, NDC 00270-1315-25
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 50 mL single dose vial, 10 count, NDC 00270-1315-30
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 500 mL imaging bulk package glass bottle, 6 count, NDC 00270-1315-95
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 75 mL single dose glass bottle, 10 count, NDC 00270-1315-47 - discontinued
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 100 mL single dose glass bottle, 10 count, NDC 00270-1316-35
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 125 mL single dose glass bottle, 10 count, NDC 00270-1316-04
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 150 mL single dose glass bottle, 10 count, NDC 00270-1316-37
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 200 mL imaging bulk package glass bottle, 10 count, NDC 00270-1316-45
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 50 mL single dose vial, 10 count, NDC 00270-1316-30
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 500 mL imaging bulk package glass bottle, 6 count, NDC 00270-1316-95
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 75 mL single dose glass bottle, 10 count, NDC 00270-1316-52
    • Isovue-M 200 intrathecal solution for injection, Bracco Diagnostics, 41%, 10 mL single dose vial, 10 count, NDC 00270-1411-11
    • Isovue-M 200 intrathecal solution for injection, Bracco Diagnostics, 41%, 20 mL single dose vial, 10 count, NDC 00270-1411-25
    • Isovue-M 300 intrathecal solution for injection, Bracco Diagnostics, 61%, 15 mL single dose vial, 10 count, NDC 00270-1412-15

Reason for the Shortage

    • Iohexol (Omnipaque - GE Healthcare) injection is currently in shortage due to the shutdown of a production facility in Shanghai, China during a COVID-19 lockdown. The facility is open again and production is operating at full capacity. As a result of the iohexol shortage, other contrast agents may be affected as organizations seek suitable alternatives. https://www.ge.com/news/press-releases/ge-healthcare-update-on-iodinated-contrast-media
    • Bracco has Isovue on shortage due to increased demand. Bracco is taking measures to protect Isovue inventory for customers during the current situation.

Available Products

    • There is insufficient supply for usual ordering

Estimated Resupply Dates

    • Bracco is allocating Isovue to existing customers.

Alternative Agents & Management

Updated

Updated July 25, 2022 by Leslie Jensen, PharmD, Drug Information Specialist. Created November 21, 2018 by Stephen Andrews, PharmD, BCPS, CPPS, Drug Information Specialist. © 2022, Drug Information Service, University of Utah, Salt Lake City, UT.

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Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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