11/21/2023

Promethazine Injection

Products Affected - Description

- Phenergan injection, Hikma, 25 mg/mL, 1 mL ampule, 25 count, NDC 00641-6082-25
- Phenergan injection, Hikma, 25 mg/mL, 1 mL vial, 25 count, NDC 00641-6084-25
- Phenergan injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-6085-25
- Promethazine injection, Hikma, 25 mg/mL, 1 mL ampule, 25 count, NDC 00641-1495-35
- Promethazine injection, Hikma, 25 mg/mL, 1 mL vial, 25 count, NDC 00641-0928-25
- Promethazine injection, Hikma, 50 mg/mL, 1 mL ampule, 25 count, NDC 00641-1496-35
- Promethazine injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-0929-25
- Promethazine injection, X-Gen, 25 mg/mL, 1 mL ampule, 25 count, NDC 39822-5525-03
- Promethazine injection, X-Gen, 50 mg/mL, 1 mL ampule, 25 count, NDC 39822-5550-06

Reason for the Shortage

- Hikma did not provide a reason for the shortage.
- X-Gen did not provide a reason for the shortage.

Available Products

- Phenergan injection, Hikma, 50 mg/mL, 1 mL ampule, 25 count, NDC 00641-6083-25

Estimated Resupply Dates

- Hikma has promethazine 50 mg/mL 1 mL vials on back order and the company estimates a release date of late-December 2023. The 25 mg/mL 1 mL vials and 1 mL ampules are on back order and the company estimates a release date of late-December 2023. The 50 mg/mL 1 mL ampules are on back order and the company cannot estimate a release date.
- Hikma has Phenergan 25 mg/mL 1 mL ampules on back order and the company estimates a release date of late-November to early-December 2023. The 25 mg/mL 1 mL vials and 50 mg/mL 1 mL vials are on back order and the company estimates a release date of 1st quarter 2024.
- X-Gen has promethazine 25 mg/mL 1 mL ampules and 50 mg/mL 1 mL ampules on back order and the company cannot estimate a release date.

Safety

- ISMP has a list of recommendations in the 2018-2019 Targeted Medication Safety Best Practices for Hospitals including the removal of promethazine from hospitals. Detailed information can be found at https://www.ismp.org/sites/default/files/attachments/2019-01/TMSBP-for-Hospitalsv2.pdf.

Updated

Updated November 21, 2023 by Michelle Wheeler, PharmD, Drug Information Specialist. Created September 29, 2022 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2023, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

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