Partnering with pharmacists to ensure compliance with USP Chapters <795>, < 797>, and <800> guidance is an evolving advanced pharmacy technician role. As frontline staff, pharmacy technicians have the unique opportunity to be at the forefront of leading process changes to ensure safe medication practices. This toolkit can be used as a reference for sites to develop an advanced hazardous drug compounding pharmacy technician position. It assumes knowledge of USP Chapters <795> and <797> and therefore highlights unique requirements and regulations specific to USP Chapter < 800>.