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7/19/2022

Exactamix 2400 Valve Set

Products Affected - Description

    • Exactamix 2400 Valve Set, Baxter, Product BXC724

Reason for the Shortage

    • Baxter has Exactamix valve sets in short supply due to problems obtaining resin required for manufacturing.

Available Products

    • There are no presentations available

Estimated Resupply Dates

    • Baxter plans to allocate available products to hospitals, however total product available will not meet current need.

Safety

    • Baxter has provided guidance on the Exactamix 2400 Valve Set due to the potential for the risk of incorrect final admix from leaking valves. The information can be found at: https://www.ashp.org/-/media/assets/drug-shortages/docs/FA-2022-024-baxter-exactamix-customer-letter.pdf.

Alternative Agents & Management

    • The joint guidance document on supply disruption considerations can be found here: ASHP, ASPEN, ISMP, NHIA Joint ExactaMix Valve Set Supply Disruption Considerations
    • No single strategy will work for all health-systems and all are less than ideal for providing patient care and preparing total parenteral nutrition (TPN).
    • Consider extending the use of the valve set if it's not being used for pumping lipids (up to 150L limit).
    • Consider pumping 2 days of TPN within 24 hours (e.g. set up at noon, pump that day's TPN (late) then pump the next day's TPN before noon (early). This strategy will require careful coordination of both orders and labs.
    • Consider pumping multiple days of TPN. This strategy may lead to excess waste of TPN components that are also in short supply (see American Society for Parenteral and Enteral Nutrition recommendations). https://www.nutritioncare.org/Productshortages/
    • Consider purchasing a different compounder with assured supply of components. This strategy is time consuming and costly.

Updated

Updated July 19, 2022 by Michelle Wheeler, PharmD, Drug Information Specialist. Created April 15, 2022 by Leslie Jensen, PharmD, Drug Information Specialist. © 2022, Drug Information Service, University of Utah, Salt Lake City, UT.

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Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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