Skip to main content Back to Top


Chlorothiazide Oral Suspension

Reason for the Shortage

    • Valeant could not provide a reason for the shortage.[1]

Available Products

    • Diuril oral suspension, Valeant, 250 mg / 5 mL 237 mL bottle, NDC 65649-0311-12

Estimated Resupply Dates

    • Valeant has Diuril oral suspension available.[1]

Implications for Patient Care

    • Chlorothiazide is a thiazide diuretic frequently used in pediatric patients to manage hypertension or for diuresis.[2]


    • Extemporaneously compounded chlorothiazide suspension may be a potential alternative during this shortage. Ensure appropriate compounding technique.

Alternative Agents & Management

    • Two publications are available outlining methods for compounding chlorothiazide 50 mg/mL oral suspension.[3,4]


    1. Valeant. Customer Service (personal communications). May 8, June 8, August 10, September 8, October 29, November 16 and 24, December 22, 2015; January 14, February 5, September 13, October 17, December 7, 2016; and January 4, 2017.
    2. McEvoy GK, Snow EK, Kester L, Litvak K, Miller J, Welsh OH, eds. AHFS DI (Lexi-Comp Online). Bethesda, MD: American Society of Health-System Pharmacists; 2015.
    3. Allen et al. Chlorothiazide 50 mg/mL oral suspension. International Journal of Pharmaceutical Compounding. 2014;18(4):326.
    4. Chlorothiazide. In: Nahata MC, Pai VB, eds. Pediatric Drug Formulations, 6th edition. Cincinnati, OH: Harvey Whitney Books Company; 2011.


Updated January 5, 2017 by Michelle Wheeler, PharmD, Drug Information Specialist. Created November 7, 2014 by Jane Chandramouli, PharmD, Drug Information Specialist. Copyright 2017, Drug Information Service, University of Utah, Salt Lake City, UT.


Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

« Back to Drug Shortage Product Bulletins

ahfs logo

Subscribe to AHFS Clinical Drug Information to get direct access to integrated drug shortages content, plus comprehensive and actionable drug information.