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5/31/2023

Lidocaine with Epinephrine Injection

Products Affected - Description

    • Lidocaine (with epinephrine 1:100,000) injection, Pfizer, 1%, 20 mL vial, 100 count, NDC 00409-3178-01
    • Lidocaine (with epinephrine 1:100,000) injection, Pfizer, 1%, 30 mL vial, 100 count, NDC 00409-3178-02
    • Lidocaine (with epinephrine 1:100,000) injection, Pfizer, 1%, 50 mL vial, 100 count, NDC 00409-3178-03
    • Lidocaine (with epinephrine 1:100,000) injection, Pfizer, 2%, 20 mL vial, 100 count, NDC 00409-3182-01
    • Lidocaine (with epinephrine 1:100,000) injection, Pfizer, 2%, 30 mL vial, 100 count, NDC 00409-3182-02
    • Lidocaine (with epinephrine 1:100,000) injection, Pfizer, 2%, 50 mL vial, 100 count, NDC 00409-3182-03
    • Lidocaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 50 mL vial, 100 count, NDC 00409-3177-01
    • Lidocaine (with epinephrine 1:200,000) injection, Pfizer, 1.5%, 30 mL vial, 25 count, NDC 00409-3181-01
    • Lidocaine (with epinephrine 1:200,000) injection, Pfizer, 1.5%, 5 mL glass ampule, 10 count, NDC 00409-1209-01
    • Lidocaine (with epinephrine 1:200,000) injection, Pfizer, 2%, 20 mL vial, 25 count, NDC 00409-3183-01
    • Xylocaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 50 mL vial, 25 count, NDC 63323-0481-57
    • Xylocaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 1%, 10 mL vial, 25 count, NDC 63323-0482-17
    • Xylocaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 1%, 20 mL vial, 25 count, NDC 63323-0482-27
    • Xylocaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 1%, 50 mL vial, 25 count, NDC 63323-0482-57
    • Xylocaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 2%, 20 mL vial, 25 count, NDC 63323-0483-27
    • Xylocaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 2%, 50 mL vial, 25 count, NDC 63323-0483-57
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 1%, 10 mL vial, 25 count, NDC 63323-0487-17
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 1%, 30 mL vial, sterile-pack 5 count, NDC 63323-0487-31
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 1%, 30 mL vial, 25 count, NDC 63323-0487-37
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 1.5%, 10 mL vial, 25 count, NDC 63323-0488-17
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 1.5%, 30 mL vial, 25 count, NDC 63323-0488-37
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 2%, 10 mL vial, 25 count, NDC 63323-0489-17
    • Xylocaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 2%, 20 mL vial, 25 count, NDC 63323-0489-27

Reason for the Shortage

    • Fresenius Kabi has Xylocaine with epinephrine presentations on shortage due to increased demand for the product and manufacturing delays.
    • Pfizer has lidocaine with epinephrine presentations on shortage due to manufacturing delays.

Available Products

    • There is insufficient supply for usual ordering

Estimated Resupply Dates

    • Fresenius Kabi has 0.5% Xylocaine with epinephrine (1:200,000) 50 mL vials on back order and the company estimates a release date of mid- to late-June 2023. The 1% Xylocaine with epinephrine (1:200,000) 10 mL, 20 mL, and 50 mL vials are on back order and the company estimates a release date of mid- to late-June 2023 for the 10 mL and 50 mL vials and mid-June 2023 for the 20 mL vials. The 1% Xylocaine-MPF with epinephrine (1:200,000) 10 mL and 30 mL vials are on back order and the company estimates a release date of mid-July 2023 for the 10 mL vials and late-June 2023 for the 30 ml vials. The 1% Xylocaine-MPF with epinephrine (1:200,000) 30 mL vials vials in sterile packs are on back order and the company cannot estimate a release date. The 1.5% Xylocaine with epinephrine (1:200,000) 10 mL and 30 mL vials are on back order and the company cannot estimate a release date. The 2% Xylocaine with epinephrine (1:200,000) 20 mL and 50 mL vials are on back order and the company estimates a release date of early-June 2023 for the 20 mL vials and mid- to late-June 2023 for the 50 mL vials. The 2% Xylocaine-MPF (1:200,000) 10 mL and 20 mL vials are on back order and the company estimates a release date of early-July 2023 for the 10 mL vials and early-June 2023 for the 20 mL vials. Check wholesalers for inventory.
    • Pfizer has 0.5% lidocaine (1:200,000) 50 mL vials available in limited supply. The 1% lidocaine (1:100,000) 20 mL, 30 mL, and 50 mL vials are on back order and the company estimates a release date of November 2023 for the 20 mL vials, January 2024 for the 30 mL vials, and October 2023 for the 50 mL vials. The 1.5% lidocaine (1:200,000) 5 mL glass ampules and 30 mL vials are on back order and the company estimates a release date of July 2024 for the 5 mL ampules and December 2023 for the 30 mL vials. The 2% lidocaine (1:200,000) 20 mL vials are on back order and the company estimates a release date of August 2023. The 2% lidocaine (1:100,000) 20 mL, 30 mL, and 50 mL vials are on back order and the company estimates a release date of June 2023 for the 20 mL and 50 mL vials and November 2023 for the 30 mL vials.

Updated

Updated May 31, 2023 by Michelle Wheeler, PharmD, Drug Information Specialist. Created November 16, 2011 by Jane Chandramouli, PharmD, Drug Information Specialist. © 2023, Drug Information Service, University of Utah, Salt Lake City, UT.

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